1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine

1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine - Names and Identifiers

Name	1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
Synonyms	2-Piperazin-Yl-4-(Trifluoromethyl)Pyrimidine 2-PIPERAZIN-YL-4-(TRIFLUOROMETHYL)PYRIMIDINE 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine 2-Piperazin-1-Yl-4-(Trifluoromethyl)Pyrimidine 2-(Piperazin-1-Yl)-4-(Trifluoromethyl)Pyrimidine 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine Pyrimidine, 2-(1-piperazinyl)-4-(trifluoromethyl)-
CAS	179756-91-3
InChI	InChI=1/C9H11F3N4/c10-9(11,12)7-1-2-14-8(15-7)16-5-3-13-4-6-16/h1-2,13H,3-6H2

1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine - Physico-chemical Properties

Molecular Formula	C9H11F3N4
Molar Mass	232.21
Density	1.306±0.06 g/cm3(Predicted)
Melting Point	50-52°C
Boling Point	331.3±52.0 °C(Predicted)
Flash Point	154.2°C
Vapor Presure	0.000157mmHg at 25°C
pKa	8.56±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.485

1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine - Risk and Safety

Hazard Symbols	Xi - Irritant
HS Code	29335990

1-[4-(Trifluoromethyl)Pyrimid-2-Yl]Piperazine - Introduction

1-(5-fluoromethylpyrimidin-2-yl) piperazine, also known as 1-(4-Trifluoromethylpyrimidin-2-yl) piperidine, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(piperazine) chemically belongs to heterocyclic compounds, and its molecular formula is C12H8F3N3. It is a white crystalline solid that is stable at room temperature. The compound has strong chelating and antibacterial properties.

Use:
1-piperazine has important applications in agriculture and medicine. It is used as a broad-spectrum heterocyclic fungicide, which can effectively inhibit the growth of some plant pathogenic fungi. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of biologically active molecules.

Method:
1-(piperazine) can be synthesized by the following steps:
First, 4-trifluoromethylpyrimidine and 2-cyanopiperidine are reacted under appropriate reaction conditions to produce the desired product. The specific reaction conditions and Reaction routes are different according to different research literatures.

Safety Information:
1-(piperazine) has relatively limited toxicological information, but it is considered to be a compound with low toxicity to the human body. However, as with all chemicals, appropriate safety measures are still required. Proper protective gloves, glasses and protective clothing are recommended for use and handling. Avoid inhaling its powder or vapor and take care to avoid contact with skin and eyes. If necessary, operate in a well-ventilated place and ensure proper storage.

Last Update：2024-04-09 21:01:54